Cerebrospinal fluid

The basic cerebrospinal fluid (CSF) parameters (cell count, CSF/ serum albumin ratio, glucose, lactate, immunoglobulin ratio, oligoclonal bands) are normal in CJD patients.

Detection of brain-derived proteins in CSF helps in the differential diagnosis. Currently, the detection of 14-3-3 proteins in CSF is the most important test.

If specimens are sent in for specific diagnostic testing, the NRC requests that it be notified prior to shipping

(Cramm und Schmitz et al. Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases. Mol Neurobiol 2014)

Samples sent to us

should always be accompanied by the following information:

Formular Download

Patient name, date of birth, gender, clinical diagnosis or suspected diagnosis, list of symptoms (to be completed), name and phone number of the physician sending in the samples.
< Download formular



Specific boxes must be used for shipping (shippig box for diagnostic speciemens labeled "UN number 3373").
< Zoom